Detalhe da pesquisa
1.
D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer.
Brief Bioinform
; 25(3)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38555474
2.
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19.
Proc Natl Acad Sci U S A
; 120(18): e2301775120, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094153
3.
SoCube: an innovative end-to-end doublet detection algorithm for analyzing scRNA-seq data.
Brief Bioinform
; 24(3)2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36941114
4.
Exploring the immune evasion of SARS-CoV-2 variant harboring E484K by molecular dynamics simulations.
Brief Bioinform
; 23(1)2022 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34553217
5.
D3AI-CoV: a deep learning platform for predicting drug targets and for virtual screening against COVID-19.
Brief Bioinform
; 23(3)2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35443040
6.
Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma.
Haematologica
; 109(4): 1206-1219, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37767568
7.
Dihydrocelastrol induces cell death and suppresses angiogenesis through BCR/AP-1/junb signalling in diffuse large B cell lymphoma.
Arch Biochem Biophys
; 754: 109929, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38367794
8.
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo.
Bioorg Med Chem Lett
; 98: 129590, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092072
9.
Design, synthesis and structure-activity relationship of 1,8-naphthalimide derivatives as highly potent hCYP1B1 inhibitors.
Bioorg Med Chem Lett
; 107: 129776, 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38692523
10.
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds.
J Chem Inf Model
; 64(3): 724-736, 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38206320
11.
Lost genome segments associate with trait diversity during rice domestication.
BMC Biol
; 21(1): 20, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36726089
12.
A Bioengineered Nanovesicle Vaccine Boosts T-B cell Interaction for Immunotherapy of Echinococcus multilocularis.
Angew Chem Int Ed Engl
; 63(13): e202319489, 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38308123
13.
DeepR2cov: deep representation learning on heterogeneous drug networks to discover anti-inflammatory agents for COVID-19.
Brief Bioinform
; 22(6)2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34117734
14.
Ligand-based approach for predicting drug targets and for virtual screening against COVID-19.
Brief Bioinform
; 22(2): 1053-1064, 2021 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33461215
15.
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway.
J Transl Med
; 21(1): 858, 2023 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38012658
16.
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma.
Arch Biochem Biophys
; 747: 109771, 2023 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37776936
17.
Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells.
J Chem Inf Model
; 63(15): 4780-4790, 2023 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37486605
18.
Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase.
Bioorg Med Chem
; 91: 117413, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490786
19.
Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies.
Phys Chem Chem Phys
; 25(26): 17692-17699, 2023 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37367726
20.
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment.
Acta Pharmacol Sin
; 44(6): 1122-1134, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627343